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基于人工智能的偏头痛发作预警方法综述

A Review of Migraine Attack Early Warning Methods Based on Artificial Intelligence

  • 摘要: 偏头痛发作预警通过捕捉发作前生理、行为与环境数据的动态变化,揭示潜在的前驱模式,帮助患者提前干预以减轻痛苦。近年来,受机器学习与可穿戴设备快速发展的启发,许多工作将多种数据源与人工智能模型相结合,拓展至偏头痛发作预测领域,赋予预警模型个性化、多模态感知的能力,但现有研究对基于机器学习的偏头痛预警算法的系统性分类与讨论较少。本文首先将相关方法按数据源及建模策略进行分类,阐述各类方法的技术路线,并进行优缺点评估与适用场景分析,为构建偏头痛预警系统提供方法参考。其次总结多模态融合模型、融合生理与日记数据的时间序列模型和个性化模型的优劣之处,阵发性偏头痛患者对比慢性患者基本收获更高。最后指出当前面临小样本、缺乏外部验证、评估标准不统一等困难,并提出构建标准化基准数据集、开发专用时序架构、跨亚型自适应建模及联邦学习边缘部署等未来方向。

     

    Abstract: Migraine attack early warning captures dynamic changes in physiological, behavioral, and environmental data before an attack to reveal potential prodromal patterns, helping patients intervene early to alleviate suffering. In recent years, inspired by rapid advances in machine learning and wearable devices, many studies have integrated diverse data sources with artificial intelligence models and extended them to the field of migraine attack prediction, endowing early warning models with personalized, multimodal perception capabilities. However, systematic classification and discussion of machine learning-based migraine early warning algorithms remain limited. This paper first classifies relevant methods according to data sources and modeling strategies, elaborates on their technical approaches, and evaluates their advantages, disadvantages, and applicable scenarios, thereby providing methodological references for building migraine early warning systems. Second, it summarizes the strengths and weaknesses of multimodal fusion models, time-series models integrating physiological and diary data, and personalized models, noting that patients with episodic migraine generally derive greater benefits than those with chronic migraine. Finally, it identifies current challenges such as small sample sizes, lack of external validation, and inconsistent evaluation standards, and proposes future directions including the construction of standardized benchmark datasets, development of dedicated time-series architectures, cross-subtype adaptive modeling, and federated learning with edge deployment.

     

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