Abstract: Smart phones are becoming more popular, more powerful and have a variety of sensors available to capture information from the outside world, process the data in real-time, and transfer information remotely using wireless communications. These factors make smart phones an ideal option as a “take-anywhere” physiological monitor without the need for additional hardware, and their potential has been explored for many medical tele-monitoring applications. In this paper, we describe a few methods that perceived of human activity parameters and vital signs parameters using the existing sensors of smart phones. In addition, in order to make the fusion and integration of several monitoring methods realized, we proposed a new monitoring approach and gave an integrated solution. Finally, through comparisons with the professional health equipment, the effectiveness of the approach was verified.