Abstract: With the development of science and technology, orthopedic biomaterials have evolved from traditional inert materials into targeted functional regulating materials. During their degradation, the materials can also regulate the local bone metabolism and promote bone regeneration and functional reconstruction. Therefore, the development of intelligent materials will be the hot spot and the new direction of orthopedic biomaterials research in the next decade, while multidisciplinary integration is an inevitable trend for the orthopedic clinics.