Abstract: 3D printed bone tissue model is important to the pre-operation planning, precision intraoperative location and post-surgery assessment. However, to print the same scale bone tissue model of patients depends on a series of processing from the CT image scanning, 3D reconstruction, 3D printing to post processes of the printed model. In the process, the quality of CT images and 3D reconstruction directly affects the precision and quality of the 3D printed model, especially the selection of which CT image series is a key problem that needs to be answered. Through the comparison of 3D reconstruction results between the bone series and stand series of CT images shown that the standard series produce better quality than the bone series. The conclusion is that the standard series may produce reconstructed 3D model of bone tissue in a better way than the bone series. And the conclusion provides a scientific proof for the selection of CT image series during the 3D reconstruction.