Abstract: Controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA) is a key technique for fast magnetic resonance imaging because of its high acceleration rate and high signal-to-noise ratio (SNR). Based on the traditional simultaneous multiple-slices excitation (SMS), CAIPIRINHA utilizes phase-modulated radio frequency pulse to simultaneously excite multiple slices to reduce overlaps of different excited slices in the same region, which benefits the separation of individual images with the help of prior information of coil sensitivity. CAIPIRINHA can largely reduce scanning time according to the number of simultaneously excited slices. Additionally, compared with traditional SMS, CAIPIRINHA also increases the SNR of the reconstructed images. In this paper, the principle of CAIPIRINHA was introduced and the sequence of CAIPIRINHA combined with gradient echo was presented as well as the preliminary experiment results on phantom and human brain.