Oil and gas pipelines have a wide range of layout, long span, and that makes the daily maintenance work very laborious. To improve efficiency of maintenance, an oil and gas pipeline supervision system based on unmanned aerial vehicle (UAV) aerial photography is proposed and realized in this work. The system is based on brower/server architecture, and adopts the geographic information system and cloud platform technologies, which can realize trajectory planning, mission management, unmanned aerial vehicle flight data, flight trajectory, aerial video real-time display, fault early warning and playback of historical events etc. With the implementation of the proposed system, the petrochemical maintainers can understand real-time condition of the pipelines and response to the damage or disaster more efficiently.