程控形变的血管组织工程支架进展
作者:
作者单位:

中国科学院深圳先进技术研究院

作者简介:

通讯作者:

基金项目:

伦理声明:



A Brief Overview of Programmed Deformed Scaffolds for Vascular Tissue Engineering
Author:
Ethical statement:

Affiliation:

Shenzhen Institutes of Advanced Technology (SIAT), Chinese Academy of Sciences (CAS)

Funding:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
    摘要:

    心血管疾病是当前人类生命健康的首要威胁。血管组织工程支架可用于病变血管的再生修复,为心血管疾病治疗提供了新选择。然而,现有血管组织工程支架尚面临界面适配的挑战,导致植入后易发生并发症而难以被临床转化。最近研发的具有程控形变能力的血管组织工程支架不但可动态适应不同尺寸的血管三维形态、并且可有序引导血管细胞的行为功能,为解决血管组织工程支架界面适配难题提供了新机遇。通过对程控形变血管组织工程支架最新研究进展和现存挑战的综述和展望,将有望为新一代组织工程血管支架的研发和转化提供重要启示。

    Abstract:

    Cardiovascular disease is one of leading threats to human life and health. Tissue-engineered vascular scaffolds that can assist the regeneration/repair of disordered vessels have provided promising alternatives for cardiovascular disease treatment. However, existing tissue-engineered vascular scaffolds still confront grand challenges in interfacial adaptations, resulting in high risks of complications upon implantation and unsatisfactory translational application. Recently, tissue-engineered vascular scaffolds capable of programmed deformation have been emerging. Such scaffolds can not only dynamically adapt to three-dimensional vascular shapes with varying diameters but also orderly regulate behaviors and functions of vascular cells, offering new opportunities for addressing the grand challenges of interfacial adaptations. An overview of most-updated advances and perspectives of programmed deformed scaffolds for vascular tissue engineering will provide valuable inspirations to the development and translational applications of new generation of tissue-engineered vascular scaffolds.

    参考文献
    相似文献
    引证文献
引用本文

Xuemin.程控形变的血管组织工程支架进展 [J].集成技术,

Citing format
Du Xuemin. A Brief Overview of Programmed Deformed Scaffolds for Vascular Tissue Engineering[J]. Journal of Integration Technology.

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
历史
  • 收稿日期:2023-09-25
  • 最后修改日期:2023-09-25
  • 录用日期:2024-02-22
  • 在线发布日期: 2024-02-22
  • 出版日期: