Wuhan Institute of Virology, Chinese Academy of Sciences
This project is supported by the National Natural Science Foundation of China (No. 2020YFA0907000).
Since the human civilization entered the information age, an exponential growth of digital information globally posed great challenges to data storage. Current data storage devices have many defects, such as limited data density, short lifespan, environment pollution and so on. Deoxyribonucleic acid (DNA), the natural carrier of genetic information, was proposed to be a reasonable alternative due to its high information density, robustness, long half-life and low maintenance cost. Although DNA storage currently faces the challenges of high reading and writhing costs, slow speed and high error rate, it has unique advantages in many fields, such as long-time archival storage, military data encryption and so on. The potential future directions of DNA storage mainly include applications under special scenarios such as space data center and military, encoding-decoding algorithms robust to base errors, in vivo DNA storage, information retrieval without sequencing, and integrated DNA storage system as well as a unified evaluation standard. We hope that in the future, DNA storage can achieve large-scale application, and open a new era of data storage.
史越,贾李佳,刘翟. DNA数据存储——机遇与挑战 [J].集成技术,
Shi Yue, Jia Lijia, Liu Di. DNA-Based Data Storage—Opportunities and Challenges[J]. Journal of Integration Technology.