Shenzhen Science Technology and Innovation Commission (KQTD2015033117210153) and National Science Library, Chinese Academy of Sciences (Y9KZ411003)
合成生物学是生命科学领域的一门新兴热门工程科学，其实质是在工程学思想指导下，按照特定目标理性设计、改造至从头重新合成生物体系，通过构造人工生物系统来研究生命科学中的基本问题或应对人类面临的重大挑战，其核心旨在通过研究以期理解生命本质(造物致知)和创造社会经济价值(造物致用)。合成生物技术被多国评价为未来的颠覆性技术之一。合成生物学已成为欧美等发达国家争相发展的颠覆性科技领域，在生物医学领域具有广阔的应用前景。对合成生物医学领域进行文献计量及专利分析显示：从 2014 年开始，合成生物医学相关文献及专利呈现爆发式增长，其中美国合成生物医学发展具有先发优势，成果突出，中国正处于追赶阶段，实力突出。该文开展合成生物医学应用与发展态势分析，旨在为我国合成生物医学发展及布局提供参考依据。
Synthetic biology is an emerging and popular engineering science in the field of life sciences.Its essence is to rationally design, transform and even resynthesize biological systems according to specific goals under the guidance of engineering thoughts, and to study the life sciences focusing on basic problems or major challenges of human beings by constructing artificial biological systems. The core of synthetic biology is to understand the essence of life (build to learn) and creating social and economic value (build to use) through research. Synthetic biotechnology has been evaluated by many countries as one of the disruptive technologies in the future. With broad application prospects in the biomedical field, synthetic biology has become a disruptive science and technology field that developed countries such as Europe and the United States are striving to develop. Based on bibliometrics and patent analysis of synthetic biomedicine, synthetic biomedicine-related literature and patents have shown explosive growth since 2014. The development of synthetic biomedicine in the United States has first-mover advantages, outstanding achievements, while China with outstanding strength is catching up with and surpassing by degrees. This article analyzes the development trend of synthetic biomedicine applications in order to provide a reference for the development and layout of synthetic biomedicine in China.
LI Yujuan, QIU Huabing, LIU Tianqing, et al. Analysis on the Trends of Synthetic Biology Research in Medical Applications[J]. Journal of Integration Technology,2021,10(4):3-16